Oxalyl chloride → HCID 22168546、化合物

HRID 1709942ノート

反応式

HRID 1709942 の反応式
[C:1]([CH2:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12]([O:14][CH3:15])=[O:13])=[CH:7][CH:6]=1)(O)=[O:2].C(Cl)(=O)C([Cl:19])=O>O1CCCC1>[C:12]([CH2:11][C:8]1[CH:9]=[CH:10][C:5]([CH2:4][C:1]([Cl:19])=[O:2])=[CH:6][CH:7]=1)([O:14][CH3:15])=[O:13]

参加物

4

反応物 2

HCID 65578Oxalyl chlorideHCID 14219918HCID 14219918、化合物

生成物 1

HCID 22168546HCID 22168546、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

反応条件

温度
45 °C

実験手順

A 3.04 g portion of methyl 4-carboxymethylphenylacetate, prepared above, was dissolved in 50 mL of anhydrous tetrahydrofuran. After the addition of 2.5 mL oxalyl chloride, the mixture was stirred for 4 hours. The solvents were evaporated under a stream of dry nitrogen as the flask was warmed to 45° C. Any remaining solvent or oxalyl chloride was then removed under high vacuum; the product was used without further purification.

後処理

  1. customThe solvents were evaporated under a stream of dry nitrogen as the flask
  2. customAny remaining solvent or oxalyl chloride was then removed under high vacuum
  3. customthe product was used without further purification

出典と根拠

ORDレコード
ord-c435aaf9e9a04b8aa43f3df138d6d551
出典データセット
uspto-grants-1990_08
特許番号
US04952336

反応ノート

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