Methanol → 1-[({2,5-Difluoro-4-[(2-{[(3-hydroxyazetidin-1-yl)carbonyl]amino}pyridin-4-yl)oxy]phenyl}amino)carbonyl]cyclopropanecarboxylic acid triethylamine salt

反応式

[F:1][C:2]1[CH:7]=[C:6]([O:8][C:9]2[CH:14]=[CH:13][N:12]=[C:11]([NH:15][C:16]([N:18]3[CH2:21][CH:20]([OH:22])[CH2:19]3)=[O:17])[CH:10]=2)[C:5]([F:23])=[CH:4][C:3]=1[NH:24][C:25]([C:27]1([C:30]([O:32]CC2C=CC=CC=2)=[O:31])[CH2:29][CH2:28]1)=[O:26].CO.[H][H].[CH2:44]([N:46]([CH2:49][CH3:50])[CH2:47][CH3:48])[CH3:45]>O1CCCC1.[Pd]>[CH2:44]([N:46]([CH2:49][CH3:50])[CH2:47][CH3:48])[CH3:45].[F:1][C:2]1[CH:7]=[C:6]([O:8][C:9]2[CH:14]=[CH:13][N:12]=[C:11]([NH:15][C:16]([N:18]3[CH2:19][CH:20]([OH:22])[CH2:21]3)=[O:17])[CH:10]=2)[C:5]([F:23])=[CH:4][C:3]=1[NH:24][C:25]([C:27]1([C:30]([OH:32])=[O:31])[CH2:29][CH2:28]1)=[O:26]