2-Propanethiol → Ethyl (isopropylthio)acetate
反応式
[Na].[SH:2][CH:3]([CH3:5])[CH3:4].Br[CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9]>C(O)C>[CH3:4][CH:3]([S:2][CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH3:5]参加物
5
実験手順
To sodium (4.2 g, 0.18 mol) in ethanol (100 mL) was added 2mercaptopropane (20 mL), 0.21 mol) followed by ethyl bromoacetate (10 mL, 0.090 mol). The mixture was stirred for 12 hours, concentrated, partitioned between ether and water and washed with water. The organic phase was dried over MgSO4, evaporated and distilled to afford the desired product. B.P. 58°-62° C. (1 mm).
後処理
- concentrationconcentrated
- custompartitioned between ether and water
- washwashed with water
- dry with materialThe organic phase was dried over MgSO4
- customevaporated
- distillationdistilled
出典と根拠
- ORDレコード
- ord-621540d05d9e4f92bffb5ed2715a18aa
- 出典データセット
- uspto-grants-1989_08
- 特許番号
- US04857507
反応ノート
読み込み中…