Nitrogen → N-(3-(Trimethoxysilyl)propyl)acrylamide

HRID 1723500

反応式

HRID 1723500 の反応式
N#N.[NH2:3][CH2:4][CH2:5][CH2:6][Si:7]([O:12][CH3:13])([O:10][CH3:11])[O:8][CH3:9].C[O-].[Na+].[C:17](Cl)(=[O:20])[CH:18]=[CH2:19]>C1(C)C=CC=CC=1.CO>[C:17]([NH:3][CH2:4][CH2:5][CH2:6][Si:7]([O:12][CH3:13])([O:8][CH3:9])[O:10][CH3:11])(=[O:20])[CH:18]=[CH2:19]

参加物

7

反応物 4

HCID 947NitrogenHCID 13140Acryloyl chlorideHCID 83756AminopropyltrimethoxysilaneHCID 10942334Sodium Methoxide

生成物 1

HCID 13879166N-(3-(Trimethoxysilyl)propyl)acrylamide

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 1140Toluene溶媒2 回

反応条件

温度
0 °C

実験手順

A one liter, three-necked flask equipped with a thermometer, stirring paddle, air tight stirring sleeve, N2 inlet and dropping funnel was charged with aminopropyltrimethoxysilane (100.0 g, 0.558 moles), toluene (160.1 g), sodium methoxide (33.16 g, 0.614 moles) and methanol (10.11 g). The mixture was stirred under N , atmosphere and cooled to 0° C using a dry ice/isopropanol bath. To this, 55.37 g (0.614 moles) of acrylyl chloride dissolved in 100 g of toluene was added gradually over a period of 30 minutes. The mixture was agitated for another 30 minutes. By-product sodium chloride was removed by filtration and the solvent was removed under reduced pressure to obtain acrylamidopropyltrimethoxysilane in essentially quantitative yield. Sodium nitrite (0.001 g) was added as an inhibitor.

後処理

  1. customA one liter, three-necked flask equipped with a thermometer
  2. additionwas added gradually over a period of 30 minutes
  3. stirringThe mixture was agitated for another 30 minutes
  4. customBy-product sodium chloride was removed by filtration
  5. customthe solvent was removed under reduced pressure

出典と根拠

ORDレコード
ord-4b6ce1266536461bb141d496d34ec9dd
出典データセット
uspto-grants-1989_08
特許番号
US04861906

関連ノート

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