2,6-Dipropylphenol → 2,6-Dipropyl4-propionylphenol

HRID 1727286ノート

反応式

HRID 1727286 の反応式
[C:1]([O-:5])(=O)[CH2:2][CH3:3].[Na+].[CH2:7]([C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([CH2:16][CH2:17][CH3:18])[C:11]=1[OH:19])[CH2:8][CH3:9]>OS(C(F)(F)F)(=O)=O>[CH2:16]([C:12]1[CH:13]=[C:14]([C:1](=[O:5])[CH2:2][CH3:3])[CH:15]=[C:10]([CH2:7][CH2:8][CH3:9])[C:11]=1[OH:19])[CH2:17][CH3:18]

参加物

4

反応物 2

HCID 811072,6-DipropylphenolHCID 2723816Sodium Propionate

生成物 1

HCID 113108722,6-Dipropyl4-propionylphenol

試薬・触媒・溶媒 1

HCID 62406Trifluoromethanesulfonic acid溶媒

実験手順

Sodium propanoate (0.88 g, 1.5 eq) and 2,6-dipropylphenol (1.09 g, 1.0 eq) were combined in Triflic Acid (5.0 g) as in Example 13, step 1. The resulting waxy solid was purified by chromatography on silica gel using ethyl acetate:hexanes:acetic acid (10:90:1) to give the titled phenol.

後処理

  1. customThe resulting waxy solid was purified by chromatography on silica gel

出典と根拠

ORDレコード
ord-3b0334179b264f1582ed15228403292d
出典データセット
uspto-grants-2009_02
特許番号
US07495020B2

反応ノート

読み込み中…