2,2'-Bis(bromomethyl)-1,1'-biphenyl → 2,2'-Dimethylbiphenyl

HRID 1729483ノート

反応式

HRID 1729483 の反応式
Br[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15]Br>C1COCC1>[C:10]1([CH3:15])[C:9]([C:4]2[C:3]([CH3:2])=[CH:8][CH:7]=[CH:6][CH:5]=2)=[CH:14][CH:13]=[CH:12][CH:11]=1

参加物

3

反応物 1

HCID 2519622,2'-Bis(bromomethyl)-1,1'-biphenyl

生成物 1

HCID 117972,2'-Dimethylbiphenyl

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

2,2'-Bis(bromomethyl)-1,1'-biphenyl (3.40 grams, 10 mmole) was added to the addition funnel and dissolved in 10 mL of dry THF. The dibromo compound may be obtained by the free radical catalyzed halogenation of 2,2'-bitolyl. The flask containing the dibenzophospholyl anion is chilled with a water-ice bath. The mixture was stirred vigorously as the dibromo compound was added dropwise to the chilled solution over 30 minutes. The solution color lightened by the end of the addition. The resulting mixture was allowed to stir at room temperature for an additional five hours. Methanol (5 mL) was added to quench out any remaining anion and resulted in a pale yellow mixture.

出典と根拠

ORDレコード
ord-d547631849664859b8132ec7d2eaff8c
出典データセット
uspto-grants-1994_07
特許番号
US05332846

反応ノート

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