Cuminaldehyde → 2-Nitro-1-(p-isopropylphenyl)-1-propanol

HRID 1731208

反応式

HRID 1731208 の反応式
[CH:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[O:9])=[CH:6][CH:5]=1)([CH3:3])[CH3:2].S(=O)(O)[O-].[Na+].[N+:17]([CH2:20][CH3:21])([O-:19])=[O:18].[OH-].[Na+]>O.C(O)C>[N+:17]([CH:20]([CH3:21])[CH:8]([C:7]1[CH:6]=[CH:5][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:11][CH:10]=1)[OH:9])([O-:19])=[O:18]

参加物

7

反応物 4

HCID 326CuminaldehydeHCID 6587NitroethaneHCID 14798Sodium HydroxideHCID 23665763Sodium Bisulfite

生成物 1

HCID 214957142-Nitro-1-(p-isopropylphenyl)-1-propanol

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 962Water溶媒

実験手順

The procedure of Example 1 was followed for the reaction of 74 g of p-isopropylbenzaldehyde and 57 g of sodium bisulfite with 75 g of 1-nitroethane and 40 g of sodium hydroxide. Water and ethanol served as solvents. The product weighed 41 g and was a light yellow oil which slowly crystallized on standing: ir (film) 2.85 (m), 3.35 (m), 6.5 (s), 7.2 (m), 7.35 (m), 9.5 (m), 11.95 (m) microns; nmr (CDCl3) 7.1 (4H, s), 5.0 to 4.6 (2H, m) 3.05 (1H, broad), 2.9 (1H, quintet), 1.3 (6H, d), 1.5 to 1.2 (3H, m) ppm.

後処理

  1. customslowly crystallized

出典と根拠

ORDレコード
ord-281721114edd434b9440d9fe483162d2
出典データセット
uspto-grants-1976_11
特許番号
US03995063

関連ノート

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