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Hydrochloric Acid → HCID 53838961、化合物

HRID 1732043
ノート
印刷プレビュー

反応式

HRID 1732043 の反応式
[CH3:1][C:2]([CH2:6][CH2:7][CH:8]=[C:9]([CH3:41])[CH2:10][CH2:11][CH:12]=[C:13]([CH3:40])[CH2:14][CH2:15][CH:16]=[C:17]([CH3:39])[CH2:18][CH2:19][CH:20]=[C:21]([CH3:38])[CH2:22][CH2:23][CH:24]=[C:25]([CH3:37])[CH2:26][CH2:27][CH:28]=[C:29]([CH3:36])[CH2:30][CH2:31][CH:32]=[C:33]([CH3:35])[CH3:34])=[CH:3][C:4]#[N:5].[Na].Cl>CO.C1COCC1>[CH3:1][CH:2]([CH2:6][CH2:7][CH:8]=[C:9]([CH3:41])[CH2:10][CH2:11][CH:12]=[C:13]([CH3:40])[CH2:14][CH2:15][CH:16]=[C:17]([CH3:39])[CH2:18][CH2:19][CH:20]=[C:21]([CH3:38])[CH2:22][CH2:23][CH:24]=[C:25]([CH3:37])[CH2:26][CH2:27][CH:28]=[C:29]([CH3:36])[CH2:30][CH2:31][CH:32]=[C:33]([CH3:35])[CH3:34])[CH2:3][C:4]#[N:5]
参加物実験手順後処理出典と根拠反応ノート

参加物

6

反応物 3

HCID 313Hydrochloric AcidHCID 5360545SodiumHCID 54519280HCID 54519280、化合物

生成物 1

HCID 53838961HCID 53838961、化合物収率 75.9%

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 8028Tetrahydrofuran溶媒

実験手順

21 g of 3,7,11,15,19,23,27,31-octamethyl-2,6,10,14,18,22,26,30-dotriacontaoctaenonitrile was dissolved in 250 ml of methanol and 100 ml of THF, and 24 g of metallic sodium was added. The reaction solution was stirred at room temperature for 30 minutes and was cooled with ice when foaming and heat generation were recognized. After the reaction solution was reacted for 2 hours, 500 ml of 6N hydrochloric acid was added and the reaction product was extracted by 500 ml of n-hexane. The organic layer was concentrated and the concentrate was refined by silica gel column chromatography, providing 16 g of 3,7,11,15,19,23,27,31-octamethyl-6,10,14,18,22,26,30-dotriacontaheptaenonitrile.

後処理

  1. temperaturewas cooled with ice when
  2. temperatureheat generation
  3. customAfter the reaction solution was reacted for 2 hours
  4. extractionthe reaction product was extracted by 500 ml of n-hexane
  5. concentrationThe organic layer was concentrated

出典と根拠

ORDレコード
ord-2aba0f4e60fb40e3b5d3b7b54c0076df
出典データセット
uspto-grants-1986_11
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US04624966

反応ノート

読み込み中…

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