(+-)-2-Undecanol → 2-Methanesulfonyloxyundecane

HRID 1733764ノート

反応式

HRID 1733764 の反応式
[CH3:1][S:2]([O:5][CH:6]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[CH3:7])(=[O:4])=[O:3].[CH3:16]C(O)CCCCCCCCC.CS(Cl)(=O)=O.C(N(C(C)C)CC)(C)C>C(Cl)Cl>[CH3:1][S:2]([O:5][CH:6]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH3:7])(=[O:4])=[O:3]

参加物

6

反応物 4

HCID 15448(+-)-2-UndecanolHCID 31297Methanesulfonyl chlorideHCID 81531DiisopropylethylamineHCID 14916009Decan-2-yl methanesulfonate

生成物 1

HCID 153433162-Methanesulfonyloxyundecane収率 95%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

2-Methanesulfonyloxyundecane was prepared as described for 2-methanesulfonyloxydecane from 2-undecanol (30.0 ml, 144 mmol), methanesulfonylchloride (15.5 ml, 200 mmol) and diisopropylethylamine (30.8 ml, 177 mmol) in dry CH2Cl2 (240 ml). After stirring for 3.5 hrs, the reaction was processed as previously stated but at 4 times the volumes to provide 2-methanesulfonyloxyundecane (31.35 g, 95%).

後処理

  1. custom2-Methanesulfonyloxyundecane was prepared

出典と根拠

ORDレコード
ord-9a93b1dfbcd94dc8bd0512900fdf1f9a
出典データセット
uspto-grants-1996_07
特許番号
US05531979

反応ノート

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