tert-Butylacetic acid → HCID 178442262、化合物

HRID 1737150ノート

反応式

HRID 1737150 の反応式
[CH:1]1[CH:2]=[CH:3][C:4]2[C:11](=[O:12])[C:10]([OH:13])=[CH:9][C:7](=[O:8])[C:5]=2[CH:6]=1.[CH3:14][C:15]([CH3:21])([CH3:20])[CH2:16]C(O)=O.S(O[O-])([O-])(=O)=O.[NH4+].[NH4+]>C(#N)C.O.[N+]([O-])([O-])=O.[Ag+]>[CH3:14][C:15]([CH3:21])([CH3:20])[CH2:16][C:9]1[C:7](=[O:8])[C:5]2[C:4]([C:11](=[O:12])[C:10]=1[OH:13])=[CH:3][CH:2]=[CH:1][CH:6]=2

参加物

7

反応物 3

HCID 14057tert-Butylacetic acidHCID 9855511Ammonium peroxysulphateHCID 178516607HCID 178516607、化合物

生成物 1

HCID 178442262HCID 178442262、化合物

試薬・触媒・溶媒 3

HCID 24470Silver Nitrate触媒HCID 962Water溶媒2 回HCID 6342Acetonitrile溶媒

実験手順

This compound was prepared by the general methods as described in Examples 1 to 15. Lawsone (0.15 g), 3,3-dimethylbutyric acid (0.15 g), and silver nitrate (0.15 g) were heated in a mixture of acetonitrile (5 ml) and water (5 ml) at 60-65° C. A solution of ammonium peroxysulphate (0.3 g) in water (5 ml) was added dropwise and the mixture heated for 1 hour and then processed as for Example 3 to yield the title compound . The crude product was purified on a silica gel column using 20% diethyl ether in petroleum ether eluant and recrystallised from petroleum ether to yield 38 mg of the title compound.

後処理

  1. customThis compound was prepared by the general methods
  2. temperaturethe mixture heated for 1 hour

出典と根拠

ORDレコード
ord-7b53e09bc124424688b926d1dac1b8a3
出典データセット
uspto-grants-1999_10
特許番号
US05962002

反応ノート

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