Diethyl Ether → 3-Methyl-7-(2-phenylethyl)pyrrolo[2,3-b]pyridine hydrobromide
反応式
[CH3:1][C:2]1[C:10]2[C:5](=[N:6][CH:7]=[CH:8][CH:9]=2)[NH:4][CH:3]=1.[Br:11][CH2:12][CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.CCOCC>C(#N)C>[BrH:11].[CH3:1][C:2]1[C:10]2[C:5]([N:6]([CH2:12][CH2:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH:7]=[CH:8][CH:9]=2)=[N:4][CH:3]=1参加物
5
実験手順
A solution of 0.3 g (2.3 mmol) 3-methylpyrrolo[2,3-b]pyridine and 0.5 g (2.7 mmol) (2-bromoethyl)benzene in 10 ml acetonitril was refluxed for 72 h. The solvent was evaporated and the solid that formed was treated with ether. Recrystalization from ethyl acetate gave 0.2 g (27%) of the title compound as a white solid.
後処理
- customThe solvent was evaporated
- customthe solid that formed
- customRecrystalization from ethyl acetate
出典と根拠
- ORDレコード
- ord-9bb3767162c642e5a05e45274cee7029
- 出典データセット
- uspto-grants-1995_08
- 特許番号
- US05439917
反応ノート
読み込み中…