Phosphorus sulfide (P2S5) → Tetradecanethioamide

HRID 1756984

反応式

HRID 1756984 の反応式
P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:2].[C:15]([NH2:30])(=O)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]>C1COCC1>[C:15](=[S:2])([NH2:30])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

参加物

4

反応物 2

HCID 14817Phosphorus sulfide (P2S5)HCID 69492Tetradecanamide

生成物 1

HCID 21469509Tetradecanethioamide収率 191.5%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

Phosphorus pentasulfide (9.8 g, 0. 044 mol) was added to a mixture of tetradecanamide (8.6 g, 0.04 mol) in dry THF (250 mL) and the mixture refluxed overnight, concentrated in vacuo, and heated with methanol (200 mL), filtered, and the filtrate concentrated in vacuo to yield a pale yellow solid (10.28 g, 99%) used without further purification.

後処理

  1. temperaturethe mixture refluxed overnight
  2. concentrationconcentrated in vacuo
  3. temperatureheated with methanol (200 mL)
  4. filtrationfiltered
  5. concentrationthe filtrate concentrated in vacuo

出典と根拠

ORDレコード
ord-8cd84f54b5e94abc80f94e0245c86aa6
出典データセット
uspto-grants-1995_08
特許番号
US05441975

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