Methyl iodide → HCID 178503996、化合物
反応式
[CH3:1]I.[NH2:3][C:4]([NH:6][C:7]1[CH:8]=[C:9]([CH:13]=[CH:14][CH:15]=1)[C:10]([OH:12])=[O:11])=[S:5]>O1CCCC1>[NH:3]=[C:4]([NH:6][C:7]1[CH:8]=[C:9]([CH:13]=[CH:14][CH:15]=1)[C:10]([OH:12])=[O:11])[S:5][CH3:1]参加物
4
反応条件
- 温度
- 75 °C
実験手順
Methyl iodide (18 g; 127.4 mmol; 7.93 ml) is added at ambient temperature, under an argon atmosphere, to a solution of 3-[(aminocarbothioyl)amino]benzoic acid (25 g; 127.4 mmol) in 375 ml of anhydrous tetrahydrofuran, and then the reaction mixture is heated at 75° C. for 2 hours. After cooling and concentration, the residue is taken up in ether and the precipitate formed is filtered off to yield the expected product.
後処理
- temperatureAfter cooling
- concentrationconcentration
- customthe precipitate formed
- filtrationis filtered off
出典と根拠
- ORDレコード
- ord-ff56684170c9424d8ca3e1bd96b8543d
- 出典データセット
- uspto-grants-2005_01
- 特許番号
- US06846833B2
反応ノート
読み込み中…