[CH:1]1([C:7](=O)[CH2:8][CH2:9][CH3:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:12][NH:13][CH2:14][C:15]([OH:17])=[O:16].S1C=CC=C1.C([O-])(=O)C.[K+].[H][H]>CO.[Pd]>[CH3:12][N:13]([CH:7]([CH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)[CH2:8][CH2:9][CH3:10])[CH2:14][C:15]([OH:17])=[O:16]A mixture of 130 parts of 1-cyclohexyl-1-butanone, 225 parts of methyl glycine, 2 parts of a solution of thiophene in methanol 4%, 960 parts of methanol and 200 parts of potassium acetate was hydrogenated overnight in a Parr apparatus with 5 parts of palladium-on-charcoal catalyst 10%. After the calculated amount of hydrogen was taken up, the catalyst was filtered off and the filtrate was evaporated. The residue was taken up in water and 1,1'-oxybisethane. The whole was extracted with a hydrochloric acid solution 10%. The aqueous layer was treated with a sodium hydroxide solution and the product was extracted with 1,1'-oxybisethane. The extract was dried, filtered and evaporated, yielding 46 parts (22.4%) of methyl N-(1-cyclohexylbutyl)glycine as a residue (int. 3).
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