Diisopropylethylamine → {(2S,3S)-3-hydroxy-2-[2-(4-trifluoromethyl-1H-benzoimidazol-2-yl)-acetylamino]-hex-4-ynyl}-carbamic acid benzyl ester

反応式

[CH2:1]([O:8][C:9](=[O:19])[NH:10][CH2:11][C@H:12]([NH2:18])[C@@H:13]([OH:17])[C:14]#[C:15][CH3:16])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Li].[F:21][C:22]([F:37])([F:36])[C:23]1[C:31]2[N:30]=[C:29]([CH2:32][C:33](O)=[O:34])[NH:28][C:27]=2[CH:26]=[CH:25][CH:24]=1.C(N(CC)C(C)C)(C)C.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F>C(Cl)Cl.CN(C=O)C>[CH2:1]([O:8][C:9](=[O:19])[NH:10][CH2:11][C@H:12]([NH:18][C:33](=[O:34])[CH2:32][C:29]1[NH:28][C:27]2[CH:26]=[CH:25][CH:24]=[C:23]([C:22]([F:36])([F:37])[F:21])[C:31]=2[N:30]=1)[C@@H:13]([OH:17])[C:14]#[C:15][CH3:16])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1