Acetonitrile → tert-Butyl 4-(6-(5-(cyanomethyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-c]pyridin-3-yl)pyridin-2-yl)piperazine-1-carboxylate

反応式

C([Li])CCC.[C:6](#[N:8])[CH3:7].[C:9]([O:13][C:14]([N:16]1[CH2:21][CH2:20][N:19]([C:22]2[CH:27]=[CH:26][CH:25]=[C:24]([C:28]3[C:36]4[C:31](=[CH:32][N:33]=[C:34](Br)[CH:35]=4)[N:30]([CH:38]4[CH2:43][CH2:42][CH2:41][CH2:40][O:39]4)[N:29]=3)[N:23]=2)[CH2:18][CH2:17]1)=[O:15])([CH3:12])([CH3:11])[CH3:10].[NH4+].[Cl-]>CCCCCC.O1CCCC1>[C:6]([CH2:7][C:34]1[CH:35]=[C:36]2[C:28]([C:24]3[N:23]=[C:22]([N:19]4[CH2:20][CH2:21][N:16]([C:14]([O:13][C:9]([CH3:12])([CH3:10])[CH3:11])=[O:15])[CH2:17][CH2:18]4)[CH:27]=[CH:26][CH:25]=3)=[N:29][N:30]([CH:38]3[CH2:43][CH2:42][CH2:41][CH2:40][O:39]3)[C:31]2=[CH:32][N:33]=1)#[N:8]