HCID 22042477、化合物 → HCID 22042441、化合物

HRID 1790887ノート

反応式

HRID 1790887 の反応式
[CH3:1][C:2]1([C:7]2(/[CH:10]=[CH:11]/[C:12](=[O:14])[CH3:13])[CH2:9][CH2:8]2)[O:6][CH2:5][CH2:4][O:3]1.[H][H]>C1COCC1.[Pt](=O)=O>[CH3:1][C:2]1([C:7]2([CH2:10][CH2:11][C:12](=[O:14])[CH3:13])[CH2:9][CH2:8]2)[O:3][CH2:4][CH2:5][O:6]1

参加物

5

反応物 2

HCID 22042477HCID 22042477、化合物HCID 178418361HCID 178418361、化合物

生成物 1

HCID 22042441HCID 22042441、化合物

試薬・触媒・溶媒 2

HCID 345198Adams' catalyst触媒HCID 8028Tetrahydrofuran溶媒

実験手順

1.23 g of 153 is dissolved in THF, and 200 mg of platinum(IV) oxide is added in an argon stream. Using a hydrogenating apparatus, it is hydrogenated until no more hydrogen is consumed, flushed with nitrogen, filtered and concentrated by evaporation. The residue is chromatographed on silica gel with ethyl acetate/hexane, whereby 1.19 g of title compound 154 accumulates as a colorless oil.

後処理

  1. customis consumed
  2. customflushed with nitrogen
  3. filtrationfiltered
  4. concentrationconcentrated by evaporation
  5. customThe residue is chromatographed on silica gel with ethyl acetate/hexane, whereby 1.19 g of title compound 154 accumulates as a colorless oil

出典と根拠

ORDレコード
ord-94c948cc57194278aef42c5ab3b35ba8
出典データセット
uspto-grants-2006_07
特許番号
US07071344B1

反応ノート

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