Benzil → Hydrobenzoin

HRID 1796957

反応式

HRID 1796957 の反応式
[C:1]1([C:7]([C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:10])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[BH4-].[Na+]>CCO.O>[C:11]1([CH:9]([CH:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[OH:8])[OH:10])[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

参加物

5

反応物 2

HCID 8651BenzilHCID 4311764Sodium borohydride

生成物 1

HCID 95447Hydrobenzoin

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 962Water溶媒

反応条件

温度
2.5 °C

実験手順

To a slurry of 97.0 g of benzil in 1 liter of 95% EtOH was added 20 g of sodium borohydride. After stirring 10 minutes, the mixture was diluted with 1 liter of water and the mixture was treated with activated carbon. The mixture was then filtered trough supercel and the filtrate heated and diluted with an additional 2 liters of water until it became slightly cloudy. The mixture was then cooled to 0 to 5° C. and the resulting crytals were collected and washed with cold water. The crystals were then dried in vacuo.

後処理

  1. additionthe mixture was treated with activated carbon
  2. filtrationThe mixture was then filtered trough supercel
  3. temperaturethe filtrate heated
  4. additiondiluted with an additional 2 liters of water until it
  5. customthe resulting crytals were collected
  6. washwashed with cold water
  7. customThe crystals were then dried in vacuo

出典と根拠

ORDレコード
ord-7f1fdae056914c53929bc0162e0ff096
出典データセット
uspto-grants-2006_04
特許番号
US07034026B2

関連ノート

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