Phenacyl bromide → HCID 178444626、化合物
反応式
C#CCCCCC=O.c1ccc(C(=O)CBr)cc1>C[C@@H]1[NH2+][C@@H](C(C)(C)C)N(C)C1=O.[O-]S(=O)(=O)C(F)(F)F.CCN(CC)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](CC)CC)C=C3O2)C4=CC=CC=C4C(=O)O.[Cl-].CN(C)C=O.Cc1cccc(C)n1>C#CCCC[C@@H](C=O)CC(=O)c1ccccc1.C#CCCC[C@H](C=O)CC(=O)c1ccccc1参加物
8
反応物 3
生成物 2
試薬・触媒・溶媒 3
反応条件
- 温度
- 22 °C
後処理
- aliquot4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN
- addition4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN
- additionchiral resolving regent (150 mM in DCM, 40 uL)
- additionCuI with DIPEA (400 mM in ACN) 40 uL
- additioninternal standard 1-phenylprop-2-yn-1-ol (4) (25 mM in ACN) 40 uL
- stirring手順は記録されていません
- aliquotAfter the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate
- additionAfter the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate and diluted with 190 uL ACN before the IM-MS analysis
出典と根拠
- ORDレコード
- ord-0e02dc590c5446e1a0d59ff069fc2f58
- 出典データセット
- Dataset from `Ultra-high-throughput mapping of the chemical space of asymmetric catalysis enables accelerated reaction discovery`
反応ノート
読み込み中…