Chlorotrimethylsilane → [(1-Ethyl-1-propen-1-yl)oxy]trimethylsilane
反応式
[CH3:1][Si:2]([CH3:5])([CH3:4])Cl.[CH2:6]([C:8]([CH2:10][CH3:11])=[O:9])[CH3:7]>>[CH3:1][Si:2]([CH3:5])([CH3:4])[O:9][C:8]([CH2:10][CH3:11])=[CH:6][CH3:7]参加物
3
実験手順
From reaction between diethylketone and trimethylchlorosilane to form 3-trimethylsilyloxy-2-pentene (1.2.4.17). This product was reacted with 1-fluoro-pyridinium triflate (1.2.4.5) to obtain 2-fluoro-3-pentanone (1.2.4.9). After bromination with pyridinium bromide followed by reduction using diborane 2-fluoro-4-bromopentane-3-ol (1.2.4.18) was obtained. Reaction of this product with sodium methylate yielded the title compound (1.2.4.16).
出典と根拠
- ORDレコード
- ord-30159976a8ee4e9f93a3fe9f35ed1325
- 出典データセット
- uspto-grants-2005_04
- 特許番号
- US06881732B2
反応ノート
読み込み中…