HCID 202244、化合物 → HCID 13135811、化合物
反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10]2[CH:15]=[CH:14][C:13]([NH2:16])=[CH:12][CH:11]=2)=[CH:4][CH:3]=1>O1CCCC1.[Pd]>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][C:10]2[CH:11]=[CH:12][C:13]([NH2:16])=[CH:14][CH:15]=2)=[CH:6][CH:7]=1参加物
4
実験手順
3.46 g of 4-[2-(4-fluoro-phenyl)-vinyl]-phenylamine is dissolved in 100 ml of tetrahydrofuran, treated with 350 mg of palladium 10% on charcoal and hydrogenated at room temperature and normal pressure for about 4 h. The catalyst is filtered off and the filtrate concentrated to yield 3.46 g (99%) of a yellow solid. MS: m/e=216.9 (M++H).
後処理
- filtrationThe catalyst is filtered off
- concentrationthe filtrate concentrated
出典と根拠
- ORDレコード
- ord-dc563ef7b2934bf993366703aedebf4f
- 出典データセット
- uspto-grants-2006_05
- 特許番号
- US07053245B2
反応ノート
読み込み中…