Ethylamine → N-Ethyl-1-naphthalenamine

HRID 1833973

反応式

HRID 1833973 の反応式
[C:1]1(O)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.P(OCCCC)(OCCCC)OCCCC.[CH2:28]([NH2:30])[CH3:29].[OH-].[Na+]>>[CH2:28]([NH:30][C:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1)[CH3:29]

参加物

5

反応物 4

HCID 6341EthylamineHCID 70051-NaphtholHCID 7623Tributyl phosphiteHCID 14798Sodium Hydroxide

生成物 1

HCID 67043N-Ethyl-1-naphthalenamine収率 85%

実験手順

288 parts of α-naphthol, 10 parts of tributyl phosphite and 110 parts of ethylamine gas are heated for 20 hours at 240° C, whilst stirring. After cooling and letting down the autoclave, the mixture is stirred for 20 minutes with 1,000 parts of 2.5 percent strength by weight aqueous sodium hydroxide solution at 70° C. The organic phase is separated off, washed with 2,000 parts of water at 30° C, separated off and distilled. 290 parts of N-ethyl-α-naphthylamine boiling at 119° - 120° C/0.1 mm Hg are obtained, corresponding to a yield of 85% of theory.

後処理

  1. temperatureAfter cooling
  2. customThe organic phase is separated off
  3. washwashed with 2,000 parts of water at 30° C
  4. customseparated off
  5. distillationdistilled

出典と根拠

ORDレコード
ord-df02dd5d1af64774bcb18913ed6bd0e8
出典データセット
uspto-grants-1978_01
特許番号
US04067903

関連ノート

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