Sodium Hydroxide → 2-Methoxy-6-methyl-4-pyridinecarboxylic acid sodium salt

HRID 1838265ノート

反応式

HRID 1838265 の反応式
[OH-].[Na+:2].C([O:5][C:6]([C:8]1[CH:13]=[C:12]([CH3:14])[N:11]=[C:10]([O:15][CH3:16])[CH:9]=1)=[O:7])C>C1COCC1>[Na+:2].[CH3:16][O:15][C:10]1[CH:9]=[C:8]([C:6]([O-:7])=[O:5])[CH:13]=[C:12]([CH3:14])[N:11]=1

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 45076200Ethyl 2-methoxy-6-methylisonicotinate

生成物 1

HCID 691079312-Methoxy-6-methyl-4-pyridinecarboxylic acid sodium salt

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

A 6.1 ml portion of 1 N aqueous sodium hydroxide was added to 10 ml of THF containing 1.20 g of 2-methoxy-6-methyl-4-pyridinecarboxylic acid ethyl ester and stirred at room temperature for 1 hour and 20 minutes, and then the reaction solvent was evaporated to obtain 2-methoxy-6-methyl-4-pyridinecarboxylic acid sodium salt. Thereafter, the title compound was obtained by the same procedure of Example 18-1.

後処理

  1. customthe reaction solvent was evaporated

出典と根拠

ORDレコード
ord-4396968ef0554a6c93e51ad6b622e0b2
出典データセット
uspto-grants-2004_01
特許番号
US06673799B1

反応ノート

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