Sodium Hydroxide → HCID 54569489、化合物
反応式
[H-].[Na+].[Br:3][C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[CH:10]=[C:9]([OH:14])[CH:8]=[CH:7]2.Br[CH2:16][CH2:17][O:18][CH3:19].[OH-:20].[Na+]>CN(C)C=O>[Br:3][C:4]1[CH:13]=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:14][CH2:16][CH2:17][O:18][CH3:19])[CH:10]=2)[C:5]=1[OH:20]参加物
6
実験手順
Sodium hydride (60%, 5.3 g, 134 mmol) was added in small portions to a mixture of 6-bromo-2-naphthol (25.0 g, 112 mmol), 2-bromoethylmethylether (17.1 g, 123 mmol) and dimethylformamide (150 ml). The mixture was stirred at room temperature for 5 h. Aqueous sodium hydroxide (200 ml, 1 M) was added, and the mixture was allowed to stir overnight. The crystals were filtered. Yield 28.2 g, 89%. Mp 54-55° C.
後処理
- stirringto stir overnight
- filtrationThe crystals were filtered
出典と根拠
- ORDレコード
- ord-f412460775aa49c69eddb5d475d3b216
- 出典データセット
- uspto-grants-2004_01
- 特許番号
- US06680328B2
反応ノート
読み込み中…