Nitromethane → 3,4-Dichloro-beta-nitrostyrene

HRID 1843926ノート

反応式

HRID 1843926 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH:5]=O.[N+:11]([CH3:14])([O-:13])=[O:12].[OH-].[Na+]>C(O)C>[Cl:10][C:9]1[CH:8]=[CH:7][C:4]([CH:5]=[CH:14][N+:11]([O-:13])=[O:12])=[CH:3][C:2]=1[Cl:1]

参加物

5

反応物 3

HCID 6375NitromethaneHCID 14798Sodium HydroxideHCID 227103,4-Dichlorobenzaldehyde

生成物 1

HCID 2362903,4-Dichloro-beta-nitrostyrene収率 75%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Using an analogous reaction procedure and workup as described in Example 1, 3,4-dichloro-benzaldehyde (5.6 g, 41.481=01) in ethanol (56 mL) was reacted with nitro methane (2.3 mL, 41.481 mmol), 10N NaOH solution (1.65 g, 41.481 mmol) at 0° C. for 1 hour to afford 5.1 g of the product (75% yield).

後処理

  1. customan analogous reaction procedure

出典と根拠

ORDレコード
ord-43a052d35d11408fbad1b69a26940f9a
出典データセット
uspto-grants-2015_02
特許番号
US08946260B2

反応ノート

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