Nitromethane → 1,2-Dichloro-4-[(E)-2-nitroethenyl]benzene
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH:5]=O.[N+:11]([CH3:14])([O-:13])=[O:12].[OH-].[Na+]>C(O)C>[Cl:10][C:9]1[CH:8]=[CH:7][C:4](/[CH:5]=[CH:14]/[N+:11]([O-:13])=[O:12])=[CH:3][C:2]=1[Cl:1]参加物
5
実験手順
Using analogous conditions and workup as described for the preparation of intermediate I-1a above, 3,4-dichlorobenzaldehyde (10 g, 74.074 mmol) in ethanol (100 mL) was reacted with nitro methane (4.12 mL, 74.074 mmol) and 10N NaOH (2.96 g in 7.4 mL of H2O, 74.074 mmol) to afford 6.2 g of the product (39% yield).
後処理
- customas described for the preparation of intermediate
出典と根拠
- ORDレコード
- ord-c74a5dc2564f4166bbc319471dbfdaad
- 出典データセット
- uspto-grants-2015_02
- 特許番号
- US08946260B2
反応ノート
読み込み中…