Acetophenone → HCID 18690517、化合物
反応式
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)(=[O:3])[CH3:2].[H-].[Na+].[C:12](OC)(=[O:20])[CH2:13][CH2:14][CH2:15][C:16]([CH3:19])([CH3:18])[CH3:17]>>[C:4]1([C:1](=[O:3])[CH2:2][C:12]([CH2:13][CH2:14][CH2:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:20])[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1参加物
4
実験手順
Other hindered beta-diketones may be prepared by the method of Example A of U.S. Pat. No. 4,065,502. Alternatively, a preferred method of preparation is the condensation of acetophenone with an appropriate methyl ester in an aromatic hydrocarbon solvent using excess sodium hydride as base. Thus, methyl neooctanoate is condensed with acetophenone to give 1-phenyl-3-neoheptyl-1,3-propanedione, and methyl 2,2-dimethyl octanoate is condensed with acetophenone to give 1-phenyl-4,4-dimethyl-1,3-decanedione, in which the product is a mixture of branched chain isomers.
後処理
- custommay be prepared by the method of Example A of U.S