Adenine → 9-(2-Hydroxypropyl)adenine, (R)-

HRID 1890234

反応式

HRID 1890234 の反応式
C1(=O)[O:6][C@H:4]([CH3:5])[CH2:3]O1.[N:8]1[C:16]([NH2:17])=[C:15]2[C:11]([N:12]=[CH:13][NH:14]2)=[N:10][CH:9]=1.[OH-].[Na+]>CN(C)C=O>[OH:6][C@H:4]([CH3:5])[CH2:3][N:12]1[CH:13]=[N:14][C:15]2[C:11]1=[N:10][CH:9]=[N:8][C:16]=2[NH2:17]

参加物

5

反応物 3

HCID 190AdenineHCID 14798Sodium HydroxideHCID 641813(4R)-4-methyl-1,3-dioxolan-2-one

生成物 1

HCID 4452119-(2-Hydroxypropyl)adenine, (R)-

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

To a reaction vessel containing inert atmosphere, e.g., nitrogen, was added carbonate (A), adenine, N,N-dimethylformamide (DMF) and catalytic amount of base such as sodium hydroxide, then (R)-9-(2-hydroxypropyl)adenine (B) was obtained;

後処理

  1. additionTo a reaction vessel containing inert atmosphere, e.g., nitrogen

出典と根拠

ORDレコード
ord-1ab64f49e11a45adab32092bff058fa2
出典データセット
uspto-grants-2013_08
特許番号
US08507463B2

関連ノート

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