Hydrochloric Acid → HCID 14576890、化合物

HRID 1904619ノート

反応式

HRID 1904619 の反応式
[CH3:1][O:2][C:3]1[CH:16]=[CH:15][C:6]([C:7]([CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])=[O:8])=[CH:5][CH:4]=1.[OH-].[Na+].[BH4-].[Na+].Cl>O>[OH:8][CH:7]([C:6]1[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:16][CH:15]=1)[CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 2668175-(4-Methoxyphenyl)-5-oxopentanoic acidHCID 4311764Sodium borohydride

生成物 1

HCID 14576890HCID 14576890、化合物収率 98.2%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To 4.44 g of 4-(4-methoxybenzoyl)butanoic acid was added a solution of 0.8 g of sodium hydroxide in 30 ml of water, and to this solution was added 1.5 g of sodium borohydride, followed by stirring of the mixture at room temperature for 24 hours. The mixture was neutralized with diluted hydrochloric acid, extracted with ether, washed with water and dried, followed by evaporation of the solvent to give 4.4 g of 5-hydroxy-5-(4-methoxyphenyl)pentanoic acid as yellow oily product.

後処理

  1. extractionextracted with ether
  2. washwashed with water
  3. customdried
  4. customfollowed by evaporation of the solvent

出典と根拠

ORDレコード
ord-83207683d7da42e3a75ebbd57cdb8930
出典データセット
uspto-grants-1989_06
特許番号
US04839360

反応ノート

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