HCID 14180568、化合物 → 2H-1,3-Benzodioxole-4,7-dione
反応式
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[C:11]2[O:16][CH2:17][O:18][C:10]=12)C1C=CC=CC=1>O1CCCC1.[Pd]>[CH2:17]1[O:16][C:11]2[C:12](=[O:15])[CH:13]=[CH:14][C:9](=[O:8])[C:10]=2[O:18]1参加物
4
実験手順
A solution of 4-benzyloxy-2,3-methylenedioxyphenol (7.7 g) in tetrahydrofuran (50 ml) was hydrogenated at atmospheric pressure over palladium-on-carbon overnight. The catalyst was removed by filtration, and the resulting hydroquinone intermediate was oxidized in actonitrile solution with ceric ammonium nitrate (25 g). After 5 minutes the reaction was quenched with water and extracted with ethyl acetate. Evaporation of the organic extract and chromatography afforded 4.9 g of 2,3-methylenedioxy-1,4-benzoquinone, mp 106°-7° C.
後処理
- customThe catalyst was removed by filtration
- customAfter 5 minutes the reaction was quenched with water
- extractionextracted with ethyl acetate
- customEvaporation of the
- extractionorganic extract
出典と根拠
- ORDレコード
- ord-becab1f0c62a478b88ab4f9f29948c80
- 出典データセット
- uspto-grants-1989_06
- 特許番号
- US04840965
反応ノート
読み込み中…