5-Benzylidenehydantoin → 5-(Phenylmethyl)-2,4-imidazolidinedione

HRID 1905814

反応式

HRID 1905814 の反応式
[CH:1](=[C:8]1[NH:12][C:11](=[O:13])[NH:10][C:9]1=[O:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>[OH-].[Na+].[Pd]>[CH2:1]([CH:8]1[NH:12][C:11](=[O:13])[NH:10][C:9]1=[O:14])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

4

反応物 1

HCID 978575-Benzylidenehydantoin

生成物 1

HCID 735655-(Phenylmethyl)-2,4-imidazolidinedione収率 79%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 14798Sodium Hydroxide溶媒

実験手順

190 g (1 mole) of 5-benzylidene-hydantoin are dissolved in 2 l of a N sodium hydroxide solution and 40 g of 5% palladium/charcoal catalyst are added. The mixture is hydrogenated at room temperature under atmospheric pressure and under shaking for 4 hours. The reaction mixture is worked up according to Example 6. Thus 150.2 g of the desired compound are obtained, yield 79%. Mp.: 187°-189° C.

後処理

  1. additionare added
  2. customis hydrogenated at room temperature under atmospheric pressure

出典と根拠

ORDレコード
ord-62ca1d88ee36474f8fd304eef8129797
出典データセット
uspto-grants-1987_03
特許番号
US04647694

関連ノート

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