反応式
O[CH2:2][C:3]1[N:4]=[CH:5][C:6]2[NH:7][C:8]3[C:13]([C:14]=2[CH:15]=1)=[CH:12][CH:11]=[CH:10][CH:9]=3.S(Cl)([Cl:18])=O>>[Cl:18][CH2:2][C:3]1[N:4]=[CH:5][C:6]2[NH:7][C:8]3[C:13]([C:14]=2[CH:15]=1)=[CH:12][CH:11]=[CH:10][CH:9]=3参加物
3
実験手順
The 3-(hydroxymethyl)-β-carboline was added to an excess (3 grams) of thionyl chloride and the mixture was refluxed for 1 hour. The excess thionyl chloride was then evaporated and the obtained residue was crystallized from hexane. 2.5 grams of 3-(chloromethyl)-β-carboline was obtained.
後処理
- temperaturethe mixture was refluxed for 1 hour
- customThe excess thionyl chloride was then evaporated
- customthe obtained residue was crystallized from hexane
出典と根拠
- ORDレコード
- ord-8d8756721e9a4063a0fb838495571a2c
- 出典データセット
- uspto-grants-2013_12
- 特許番号
- US08614319B2
関連ノート
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