Diethylamine → (R)-4-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-{(S)-1-[1-(1-hydroxy-2-methoxycarbonyl-ethyl)-cyclopropylcarbamoyl]-2-tritylsulfanyl-ethylcarbamoyl}-butyric acid tert-butyl ester

反応式

[CH3:1][O:2][C:3](=[O:53])[CH2:4][CH:5]([C:7]1([NH:10][C:11](=[O:52])[C@H:12]([NH:34][C:35](OCC2C3C=CC=CC=3C3C2=CC=CC=3)=[O:36])[CH2:13][S:14][C:15]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH2:9][CH2:8]1)[OH:6].C(NCC)C.C1CN([P+](ON2N=N[C:78]3[CH:79]=[CH:80][CH:81]=[CH:82][C:77]2=3)(N2CCCC2)N2CCCC2)CC1.F[P-](F)(F)(F)(F)F.[NH:92]([C:106]([O:108][CH2:109][CH:110]1C2C(=CC=CC=2)[C:116]2[C:111]1=[CH:112][CH:113]=[CH:114][CH:115]=2)=[O:107])[C@@H:93](C(O)=O)[CH2:94][CH2:95][C:96](=[O:102])[O:97][C:98]([CH3:101])([CH3:100])[CH3:99].C(N(C(C)C)CC)(C)C>CC#N.C(Cl)Cl>[C:98]([O:97][C:96](=[O:102])[CH2:95][CH2:94][C@@H:93]([NH:92][C:106]([O:108][CH2:109][CH:110]1[C:78]2[CH:79]=[CH:80][CH:81]=[CH:82][C:77]=2[C:112]2[C:111]1=[CH:116][CH:115]=[CH:114][CH:113]=2)=[O:107])[C:35](=[O:36])[NH:34][C@@H:12]([C:11](=[O:52])[NH:10][C:7]1([CH:5]([OH:6])[CH2:4][C:3]([O:2][CH3:1])=[O:53])[CH2:9][CH2:8]1)[CH2:13][S:14][C:15]([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)([CH3:101])([CH3:99])[CH3:100]