Phosphorus pentachloride → (4-Cyanophenyl)methanesulfonyl chloride
反応式
[Na].[C:2]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][S:11]([OH:14])(=O)=[O:12])=[CH:6][CH:5]=1)#[N:3].P(Cl)(Cl)(Cl)(Cl)[Cl:16]>C(#N)C>[C:2]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][S:11]([Cl:16])(=[O:14])=[O:12])=[CH:6][CH:5]=1)#[N:3]参加物
5
実験手順
A suspension of 1.1 g (5.02 mMol) of the sodium salt of 4-cyanobenzenemethanesulphonic acid in 20 ml of acetonitrile was mixed with 1.2 g (5.76 mMol) of phosphorus-(V)-chloride and then refluxed for 24 hours. The insoluble matter was filtered off and the filtrate was evaporated down in vacuo. Yield; 0.8 g (74% of theory). The product was used in the next step without purification.
後処理
- temperaturerefluxed for 24 hours
- filtrationThe insoluble matter was filtered off
- customthe filtrate was evaporated down in vacuo
- customThe product was used in the next step without purification
出典と根拠
- ORDレコード
- ord-a5e0cd29cb304df0be7bd304719ca75e
- 出典データセット
- uspto-grants-2000_09
- 特許番号
- US06114390
反応ノート
読み込み中…