Allyl bromide → 4-Allyloxy-2,5-dichloronitrobenzene
反応式
[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[C:5]([Cl:11])=[CH:4][C:3]=1[OH:12].C(=O)([O-])[O-].[K+].[K+].[CH2:19](Br)[CH:20]=[CH2:21]>C(#N)C>[CH2:21]([O:12][C:3]1[C:2]([Cl:1])=[CH:7][C:6]([N+:8]([O-:10])=[O:9])=[C:5]([Cl:11])[CH:4]=1)[CH:20]=[CH2:19]参加物
5
実験手順
The product of step (a) (59.3 g, 285 mmol), 550 ml acetonitrile, 43 g (314 mmol) of potassium carbonate and 27.2 ml (314 mmol) of allyl bromide were combined and heated to reflux, and then the reaction was evaporated under reduced pressure. The mixture was extracted with diethyl ether, washed with water, and separated. The organics were dried over magnesium sulfate and stripped to yield 66.1 g of 4-allyloxy-2,5-dichloronitrobenzene product.
後処理
- temperatureheated
- temperatureto reflux
- customthe reaction was evaporated under reduced pressure
- extractionThe mixture was extracted with diethyl ether
- washwashed with water
- customseparated
- dry with materialThe organics were dried over magnesium sulfate
出典と根拠
- ORDレコード
- ord-b1d3a2b801a248e68ada93e3f0958bd5
- 出典データセット
- uspto-grants-1998_07
- 特許番号
- US05786301
反応ノート
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