Hydrogen Sulfide → HCID 14447407、化合物

HRID 1973076ノート

反応式

HRID 1973076 の反応式
[C:1]1([CH:7]([C:9]([O:11][CH:12]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[O:10])[NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(O[CH:28]=[S:29])C.S>O1CCCC1>[S:29]=[CH:28][NH:8][CH:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)[C:9]([O:11][CH:12]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1)=[O:10]

参加物

5

反応物 3

HCID 402Hydrogen SulfideHCID 11073343Methanethioic acid, O-ethyl esterHCID 131710294HCID 131710294、化合物

生成物 1

HCID 14447407HCID 14447407、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

A solution of 15.9 g. (0.05 mol.) of α-phenylglycine, diphenylmethyl ester, and 9 g. (0.01 mol.) of ethylthioformate in 50 ml. of tetrahydrofuran is stirred overnight at room temperature. Then a stream of hydrogen sulfide is passed into the solution for ten minutes, the reaction mixture is permitted to stand overnight, then concentrated and petroleum ether is added to the residue. 16.9 g. of α-[(thioxomethyl)-amino]benzeneacetic acid, diphenylmethyl ester, crystallizes. The crude product is recrystalized from methanol, m.p. 129°-130°.

後処理

  1. concentrationconcentrated
  2. additionpetroleum ether is added to the residue
  3. customof α-[(thioxomethyl)-amino]benzeneacetic acid, diphenylmethyl ester, crystallizes
  4. customThe crude product is recrystalized from methanol, m.p. 129°-130°

出典と根拠

ORDレコード
ord-27ecc21f828f43b39bcfeb7d3ef8f7d5
出典データセット
uspto-grants-1976_12
特許番号
US03996219

反応ノート

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