Chloroform → HCID 18766188、化合物

HRID 19749

反応式

HRID 19749 の反応式
[NH2:1][O:2][CH2:3][CH:4]([OH:12])[CH2:5][N:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1.C(Cl)(Cl)Cl.[CH2:17]([N:24]=[C:25]=[O:26])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]>>[OH:12][CH:4]([CH2:5][N:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)[CH2:3][O:2][NH:1][C:25]([NH:24][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])=[O:26]

参加物

4

反応物 3

HCID 6212ChloroformHCID 138341n-Heptyl isocyanateHCID 187662101-(Aminooxy)-3-(piperidin-1-yl)propan-2-ol

生成物 1

HCID 18766188HCID 18766188、化合物

実験手順

To the solution of 1.23 g (7.1 mmol) of l-aminooxy-2-hydroxy-3-(1-piperidinyl)-propane dissolved in 20 ml of chloroform 1.0 g (7.1 mmol) of heptyl isocyanate was added and the reaction mixture was stirred for 20 hours. Solvent was evaporated in vacuum and the residue was purified by chromatography to give pure colorless oil. White crystalline product was obtained by triturating with petroleum ether.

後処理

  1. additionwas added
  2. customSolvent was evaporated in vacuum
  3. customthe residue was purified by chromatography
  4. customto give pure colorless oil
  5. customWhite crystalline product was obtained
  6. customby triturating with petroleum ether

出典と根拠

ORDレコード
ord-5d41a87368eb46de9294345e9b841d10
出典データセット
uspto-grants-2010_06
特許番号
US07745465B2

関連ノート

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