Azobisisobutyronitrile → Propyl maleimide t-butyl bicyclo[2,2,2]oct-5-ene-2-carboxylate 2-hydroxyethyl bicyclo[2,2,2]oct-5-ene-2-carboxylate

HRID 1975894ノート

反応式

HRID 1975894 の反応式
[CH2:1]([C:4]1[C:5]([NH:7][C:8](=[O:10])[CH:9]=1)=[O:6])[CH2:2][CH3:3].[CH:11]12[CH2:18][CH2:17][CH:14]([CH:15]=[CH:16]1)[CH2:13][CH:12]2[C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20].[CH:26]12[CH2:33][CH2:32][CH:29]([CH:30]=[CH:31]1)[CH2:28][CH:27]2[C:34]([O:36][CH2:37][CH2:38]CO)=[O:35].N(C(C)(C)C#N)=NC(C)(C)C#N>O1CCCC1>[CH2:1]([C:4]1[C:5]([NH:7][C:8](=[O:10])[CH:9]=1)=[O:6])[CH2:2][CH3:3].[CH:11]12[CH2:18][CH2:17][CH:14]([CH:15]=[CH:16]1)[CH2:13][CH:12]2[C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20].[CH:26]12[CH2:33][CH2:32][CH:29]([CH:30]=[CH:31]1)[CH2:28][CH:27]2[C:34]([O:36][CH2:37][CH2:38][OH:6])=[O:35]

参加物

6

反応物 4

HCID 6547AzobisisobutyronitrileHCID 18413667t-Butyl bicyclo[2,2,2]oct-5-ene-2-carboxylateHCID 21880478Propyl maleimideHCID 229870623-Hydroxypropyl bicyclo[2,2,2]oct-5-ene-2-carboxylate

生成物 1

HCID 86756652Propyl maleimide t-butyl bicyclo[2,2,2]oct-5-ene-2-carboxylate 2-hydroxyethyl bicyclo[2,2,2]oct-5-ene-2-carboxylate収率 78%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

Propyl maleimide (1 mol.), t-butyl bicyclo[2,2,2]oct-5-ene-2-carboxylate (0.5 mol.) and 3-hydroxypropyl bicyclo[2,2,2]oct-5-ene-2-carboxylate (0.5 mol) were dissolved in 50 g to 300 g of tetrahydrofuran (THF), 2 g to 15 g of 2,2′-azobisisobutyronitrile (AIBN) was added thereto, and the resulting solution was reacted at a temperature between 60° C. and 70° C. in a nitrogen atmosphere for 10 hours. After a high molecular weight was achieved by the reaction, the resultant product was precipitated in an ethyl ether or hexane solvent. The gathered precipitate was dried, and the desired poly(propyl maleimide/t-butyl bicyclo[2,2,2]oct-5-ene-2-carboxylate/2-hydroxyethyl bicyclo[2,2,2]oct-5-ene-2-carboxylate) polymer was obtained at a yield of about 78%.

後処理

  1. customthe resulting solution was reacted at a temperature between 60° C. and 70° C. in a nitrogen atmosphere for 10 hours
  2. customAfter a high molecular weight was achieved by the reaction
  3. customthe resultant product was precipitated in an ethyl ether or hexane solvent
  4. customThe gathered precipitate was dried
  5. customwas obtained at a yield of about 78%

出典と根拠

ORDレコード
ord-4d0b982ccc8c4418a97df2eb09bec56b
出典データセット
uspto-grants-2001_05
特許番号
US06225020B1

反応ノート

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