Dimethylformamide → 7-bromo-N-[4-[[N-methyl-N-(tetrahydropyran-4-yl)amino]methyl]phenyl]-1,1-dioxo-2,3-dihydro-1-benzothiepine-4-carboxamide

反応式

[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[S:11](=[O:13])(=[O:12])[CH2:10][CH2:9][C:8]([C:14]([OH:16])=O)=[CH:7][C:6]=2[CH:17]=1.S(Cl)(Cl)=O.CN(C=O)C.[CH3:27][N:28]([CH2:35][C:36]1[CH:42]=[CH:41][C:39]([NH2:40])=[CH:38][CH:37]=1)[CH:29]1[CH2:34][CH2:33][O:32][CH2:31][CH2:30]1>C1COCC1.C(N(CC)CC)C>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[S:11](=[O:12])(=[O:13])[CH2:10][CH2:9][C:8]([C:14]([NH:40][C:39]3[CH:41]=[CH:42][C:36]([CH2:35][N:28]([CH3:27])[CH:29]4[CH2:34][CH2:33][O:32][CH2:31][CH2:30]4)=[CH:37][CH:38]=3)=[O:16])=[CH:7][C:6]=2[CH:17]=1