Formaldehyde → N-methyl-N-tertiarybutylaminoethoxyethanol
反応式
[C:1]([NH:5][CH2:6][CH2:7][O:8][CH:9]([OH:11])[CH3:10])([CH3:4])([CH3:3])[CH3:2].[CH2:12]=O>[Pd].CO>[CH3:12][N:5]([CH2:6][CH2:7][O:8][CH:9]([OH:11])[CH3:10])[C:1]([CH3:4])([CH3:2])[CH3:3]参加物
5
反応条件
- 温度
- 80 °C
実験手順
A total of 145 g of tertiarybutylaminoethoxyethanol, 108 g of 37% aqueous formaldehyde, 10 g of 10% Pd/C, and 1 l of methanol were charged to an autoclave, pressured up to 1000 psi with H2 and heated at 80° C. for 8 hours. Filtration and distillation of the reaction mixture yielded 128 g of N-methyl-N-tertiarybutylaminoethoxyethanol with b.p. of 128° C. at 23 mm.
後処理
- filtrationFiltration and distillation of the reaction mixture
出典と根拠
- ORDレコード
- ord-85accf3c350941e3b5cc40410d6b155b
- 出典データセット
- uspto-grants-1985_04
- 特許番号
- US04508692
反応ノート
読み込み中…