反応式
OC1C=C(C=CC=1)C=O.N1CCSCC1.[BH4-].[Na+].[S:18]1[CH2:23][CH2:22][N:21]([CH2:24][C:25]2[CH:26]=[C:27]([OH:31])[CH:28]=[CH:29][CH:30]=2)[CH2:20][CH2:19]1.Cl.Cl[CH2:34][CH2:35][CH2:36][NH2:37].[H-].[Na+]>>[S:18]1[CH2:23][CH2:22][N:21]([CH2:24][C:25]2[CH:26]=[C:27]([CH:28]=[CH:29][CH:30]=2)[O:31][CH2:34][CH2:35][CH2:36][NH2:37])[CH2:20][CH2:19]1参加物
7
実験手順
By operating as described hereinabove, by reacting 0.2 mol of 3-hydroxybenzaldehyde with 0.4 mol of thiomorpholine in the presence of 0.2 mol of sodium borohydride (as in PREPARATION 1(a) 3-thiomorpholinomethylphenol is obtained, which, treated with an excess of 3-chloropropylamine hydrochloride in the presence of sodium hydride (as in PREPARATION 1(b), gives 3-(3-thiomorpholinomethylphenoxy)propylamine, in the form of an oil.
後処理
- customis obtained
出典と根拠
- ORDレコード
- ord-56be3c1587b541558e18dc19dd2b92a3
- 出典データセット
- uspto-grants-1985_04
- 特許番号
- US04514408
関連ノート
読み込み中…