Carbon Tetrachloride → 2-Nitro-3-Methylbenzotrichloride
反応式
[N+:1]([C:4]1[C:11](C)=[CH:10][CH:9]=[CH:8][C:5]=1[CH2:6]Br)([O-:3])=[O:2].[OH-].[Na+].[C:15]([Cl:19])(Cl)([Cl:17])[Cl:16]>[Cl-].C([N+](CC)(CC)CC)C.C(Cl)Cl>[N+:1]([C:4]1[C:5]([CH3:6])=[CH:8][CH:9]=[CH:10][C:11]=1[C:15]([Cl:19])([Cl:17])[Cl:16])([O-:3])=[O:2]参加物
6
実験手順
1.5 gms of 2-nitro-3-methyl benzyl bromide was mixed with 0.05 gms of tetraethyl ammonium chloride in 15 ml of methylene chloride and 10 ml of carbon tetrachloride. 20 ml of 50% sodium hydroxide was added and the mixture refluxed for about 3 hours. After completion of the reaction, the organic layer was separated, washed with water, and the product separated to give 36% yield as determined by GC-Mass spectral analysis.
後処理
- temperaturethe mixture refluxed for about 3 hours
- customAfter completion of the reaction
- customthe organic layer was separated
- washwashed with water
- customthe product separated
- customto give 36% yield
出典と根拠
- ORDレコード
- ord-a37bb128ab504e858de531d9a4779775
- 出典データセット
- uspto-grants-1986_06
- 特許番号
- US04593144
反応ノート
読み込み中…