Sulfuric Acid → HCID 70436618、化合物

HRID 1995046ノート

反応式

HRID 1995046 の反応式
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]([NH:9][CH:10]1[C:21](=[O:22])[N:12]2[C:13]([C:18]([OH:20])=[O:19])=[C:14](Cl)[CH2:15][S:16][C@H:11]12)=[O:8].S([O-])([O-])(=O)=O.[K+].[K+].S(=O)(=O)(O)O>[I-].C([N+](CCCC)(CCCC)CCCC)CCC.[Hg].[Pt]>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]([NH:9][CH:10]1[C:21](=[O:22])[N:12]2[C:13]([C:18]([OH:20])=[O:19])=[CH:14][CH2:15][S:16][C@H:11]12)=[O:8]

参加物

7

反応物 3

HCID 1118Sulfuric AcidHCID 24507Potassium SulfateHCID 70437070HCID 70437070、化合物

生成物 1

HCID 70436618HCID 70436618、化合物

試薬・触媒・溶媒 3

HCID 23931Mercury触媒HCID 23939Platinum触媒HCID 67553Tetrabutylammonium Iodide触媒

実験手順

Fifty ml. of working fluid was prepared, containing 6.4 mg./ml. of 7-(thien-2-ylacetamido)-3-chloro-3-cephem-4-carboxylic acid in 0.25 molar pH 8 McIlvaine buffer containing 0.0375 molar tetrabutylammonium iodide. The McIlvaine buffer was prepared according to McIlvaine's article at Anal. Chem. 28, 1179 (1956). The measured pH of the working fluid was 7.3. It was transferred to the cathode compartment of an electrolysis cell having a mercury ring working electrode and a stirrer. The circular auxiliary electrode compartment was suspended over the mercury pool, and consisted of a platinum wire in toroidal shape over a 4% agar gel supported by a medium porosity sintered glass frit. The auxiliary fluid was saturated aqueous potassium sulfate. The cell was stoppered, and a deaerating frit, pH electrode, reference electrode and a delivery tube through which 2 N sulfuric acid could be added were installed. The reference electrode was a Beckman fiber-junction saturated calomel electrode.

後処理

  1. customwas prepared
  2. additioncontaining 6.4 mg
  3. customThe McIlvaine buffer was prepared

出典と根拠

ORDレコード
ord-b2755ad35b734f4daa639615b4f211b1
出典データセット
uspto-grants-1983_09
特許番号
US04402803

反応ノート

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