反応式
[NH:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]=O.[CH:8](O)=[O:9]>>[C:5]12[CH:6]=[C:2]3[N:1]=[C:5]([CH:4]=[CH:3]3)[CH:6]=[C:2]3[NH:1][C:5]([CH:4]=[CH:3]3)=[CH:6][C:2]3=[N:1][C:5]([CH:4]=[CH:3]3)=[CH:6][C:2]([NH:1]1)=[CH:3][CH:4]=2.[NH:1]1[CH:5]=[CH:4][CH:3]=[CH:2]1.[CH2:8]=[O:9]参加物
5
実験手順
The reported methods for the synthesis of porphine over the past 70 years are summarized in Table 1. Fischer and Gleim obtained 17 mg of porphine by prolonged heating of 20 g of pyrrole-2-carboxaldehyde in formic acid.6 In the same era, Rothemund obtained porphine from pyrrole and formaldehyde, albeit in very low yield (0.02%).7 The yield was increased to 0.9% by slow addition of pyrrole and formaldehyde to propionic acid.8
出典と根拠
- ORDレコード
- ord-663bc20c00f64cb7a43ef897fbd917f0
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07745618B2
関連ノート
読み込み中…