Vinyl Acetate → 3,3-Dimethyl-1-vinyloxybutane

HRID 20331

反応式

HRID 20331 の反応式
[CH3:1][C:2]([CH3:7])([CH3:6])[CH2:3][CH2:4][OH:5].[C:8](OC=C)(=O)[CH3:9].C(=O)([O-])[O-].[Na+].[Na+]>C1C=CC=CC=1.C1CC=CCCC=C1.C1CC=CCCC=C1.[Cl-].[Cl-].[Ir].[Ir]>[CH3:1][C:2]([CH3:7])([CH3:6])[CH2:3][CH2:4][O:5][CH:8]=[CH2:9]

参加物

6

反応物 3

HCID 7904Vinyl AcetateHCID 10340Sodium CarbonateHCID 122333,3-Dimethyl-1-butanol

生成物 1

HCID 663680153,3-Dimethyl-1-vinyloxybutane

試薬・触媒・溶媒 2

HCID 6436381Chloro(1,5-cyclooctadiene)iridium(I) dimer触媒HCID 241Benzene溶媒

実験手順

Add chloro(1,5-cyclooctadiene)iridium(I) dimer (0.39 g, 0.59 mmol) to 3,3-dimethylbutan-1-ol (3.00 g, 29.35 mmol), vinyl acetate (10.11 g, 117.42 mmol) and sodium carbonate (1.87 g, 17.61 mmol) in benzene (10 mL) at room temperature. Boil under nitrogen 12 hours. Cool to room temperature and filter. Distill the filtrate and collect fraction boiling ˜125° C.-130° C. Flush through a silica gel pad with hexanes and concentrate to provide the title compound.

後処理

  1. custom12 hours
  2. filtrationfilter
  3. distillationDistill the filtrate
  4. customcollect fraction
  5. customboiling ˜125° C.-130° C
  6. customFlush through a silica gel pad with hexanes
  7. concentrationconcentrate

出典と根拠

ORDレコード
ord-226ce7882d634d20897871d2dacfff1a
出典データセット
uspto-grants-2010_06
特許番号
US07745438B2

関連ノート

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