Vinyl Acetate → 3,3-Dimethyl-1-vinyloxybutane
反応式
[CH3:1][C:2]([CH3:7])([CH3:6])[CH2:3][CH2:4][OH:5].[C:8](OC=C)(=O)[CH3:9].C(=O)([O-])[O-].[Na+].[Na+]>C1C=CC=CC=1.C1CC=CCCC=C1.C1CC=CCCC=C1.[Cl-].[Cl-].[Ir].[Ir]>[CH3:1][C:2]([CH3:7])([CH3:6])[CH2:3][CH2:4][O:5][CH:8]=[CH2:9]参加物
6
実験手順
Add chloro(1,5-cyclooctadiene)iridium(I) dimer (0.39 g, 0.59 mmol) to 3,3-dimethylbutan-1-ol (3.00 g, 29.35 mmol), vinyl acetate (10.11 g, 117.42 mmol) and sodium carbonate (1.87 g, 17.61 mmol) in benzene (10 mL) at room temperature. Boil under nitrogen 12 hours. Cool to room temperature and filter. Distill the filtrate and collect fraction boiling ˜125° C.-130° C. Flush through a silica gel pad with hexanes and concentrate to provide the title compound.
後処理
- custom12 hours
- filtrationfilter
- distillationDistill the filtrate
- customcollect fraction
- customboiling ˜125° C.-130° C
- customFlush through a silica gel pad with hexanes
- concentrationconcentrate
出典と根拠
- ORDレコード
- ord-226ce7882d634d20897871d2dacfff1a
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07745438B2
反応ノート
読み込み中…