Hydrogen Bromide → Methyl 4-[(2,4-diaminopteridin-6-yl)methyl]-2,3-dihydro-1,4-benzoxazine-7-carboxylate

HRID 203390ノート

反応式

[Br:6][CH2:7][c:8]1[n:9][c:10]2[c:11]([NH2:19])[n:12][c:13]([NH2:18])[n:14][c:15]2[n:16][cH:17]1.[BrH:5].[C:38](=[O:39])([O-:40])[OH:41].[CH3:43][C:44]([N:45]([CH3:46])[CH3:47])=[O:48].[CH:1]([OH:2])([CH3:3])[CH3:4].[CH:34]([Cl:35])([Cl:36])[Cl:37].[Na+:42].[O:20]1[CH2:21][CH2:22][NH:23][c:24]2[c:25]1[cH:26][c:27]([C:30](=[O:31])[O:32][CH3:33])[cH:28][cH:29]2>>[CH2:7]([c:8]1[n:9][c:10]2[c:11]([NH2:19])[n:12][c:13]([NH2:18])[n:14][c:15]2[n:16][cH:17]1)[N:23]1[CH2:22][CH2:21][O:20][c:25]2[c:24]1[cH:29][cH:28][c:27]([C:30](=[O:31])[O:32][CH3:33])[cH:26]2