Sodium Hydroxide → (+/-)-(4-Chloro-2-{2-[2-(2,4-dimethyl-thiazol-5-yl)-cyclopropanecarbonyl]-1,2,3,4-tetrahydro-isoquinolin-1-yl}-phenoxy)-acetic acid

反応式

[CH3:1][C:2]1[S:3][C:4]([C@@H:8]2[CH2:10][C@H:9]2[C:11]([OH:13])=O)=[C:5]([CH3:7])[N:6]=1.C([O:16][C:17](=[O:37])[CH2:18][O:19][C:20]1[CH:25]=[CH:24][C:23]([Cl:26])=[CH:22][C:21]=1[CH:27]1[C:36]2[C:31](=[CH:32][CH:33]=[CH:34][CH:35]=2)[CH2:30][CH2:29][NH:28]1)C.Cl.CN(C)CCCN=C=NCC.[OH-].[Na+]>CN(C=O)C.CN(C1C=CN=CC=1)C.C(O)=O>[Cl:26][C:23]1[CH:24]=[CH:25][C:20]([O:19][CH2:18][C:17]([OH:37])=[O:16])=[C:21]([CH:27]2[C:36]3[C:31](=[CH:32][CH:33]=[CH:34][CH:35]=3)[CH2:30][CH2:29][N:28]2[C:11]([CH:9]2[CH2:10][CH:8]2[C:4]2[S:3][C:2]([CH3:1])=[N:6][C:5]=2[CH3:7])=[O:13])[CH:22]=1