Water → 5-[4-(2-Isopropyl-phenoxy)-benzylidene]-2-methylsulfanyl-thiazol-4-one

HRID 2040112

反応式

[CH:1]([C:4]1[CH:24]=[CH:23][CH:22]=[CH:21][C:5]=1[O:6][C:7]1[CH:20]=[CH:19][C:10]([CH:11]=[C:12]2[S:16][C:15](=[S:17])[NH:14][C:13]2=[O:18])=[CH:9][CH:8]=1)([CH3:3])[CH3:2].CI.[CH:27](N(C(C)C)CC)(C)C.O>C(O)C>[CH:1]([C:4]1[CH:24]=[CH:23][CH:22]=[CH:21][C:5]=1[O:6][C:7]1[CH:20]=[CH:19][C:10]([CH:11]=[C:12]2[S:16][C:15]([S:17][CH3:27])=[N:14][C:13]2=[O:18])=[CH:9][CH:8]=1)([CH3:3])[CH3:2]

参加物

実験手順

To a solution of 5-[4-(2-Isopropyl-phenoxy)-benzylidene]-2-thioxo-thiazolidin-4-one (0.4 g, 1.12 mmol) in Ethanol (14 mL) was added CH3I (0.32 g, 2.25 mmol) and diisopropylethylamine (0.17 g, 1.35 mmol). The reaction mixture was stirred at room temperature for 4 h. It was then added water (40 mL) and the slurry was stirred at room temperature for 30 minutes. The solid was filtered, washed with water to yield the 5-[4-(2-Isopropyl-phenoxy)-benzylidene]-2-methylsulfanyl-thiazol-4-one as a yellow solid (0.42 g, 94%)

後処理

filtrationThe solid was filtered
washwashed with water

出典と根拠

ORDレコード: ord-e1e78565f58b45a1a50e2094fbf2e5bf
出典データセット: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08580832B2

反応式

参加物

反応物 4

生成物 1

試薬・触媒・溶媒 1

実験手順

後処理

出典と根拠

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