Thionyl Chloride → HCID 20344102、化合物

HRID 2049630ノート

反応式

HRID 2049630 の反応式
[F:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][CH:16]=1)[O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[CH2:12]O.S(Cl)([Cl:19])=O>N1C=CC=CC=1>[Cl:19][CH2:12][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[O:5][C:4]1[CH:14]=[CH:15][CH:16]=[C:2]([F:1])[CH:3]=1

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 203440982-(3-Fluorophenoxy)benzenemethanol

生成物 1

HCID 20344102HCID 20344102、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

2-(3-Fluorophenoxy)benzenemethanol (30 g.) was mixed with 13.2 ml. of pyridine. Thionyl chloride (12.4 ml.) was added dropwise at 25°-30°, the mixture stirred 5 hours at room temperature, then partitioned between water and ether. The organic layer was washed with a 10% sodium carbonate solution, then with water, dried over sodium carbonate and evaporated to give the title compound. ##STR12##

後処理

  1. custompartitioned between water and ether
  2. washThe organic layer was washed with a 10% sodium carbonate solution
  3. dry with materialwith water, dried over sodium carbonate
  4. customevaporated

出典と根拠

ORDレコード
ord-76b9dd455a514ed2b6d700ed7ef59965
出典データセット
uspto-grants-1980_04
特許番号
US04198421

反応ノート

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