Methyl iodide → HCID 848831、化合物
反応式
[CH3:1][C:2]1[C:3](=[O:14])[NH:4][C:5]2[C:10]([N:11]=1)=[CH:9][C:8]([CH3:12])=[C:7]([CH3:13])[CH:6]=2.CI.[C:17](=O)([O-])[O-].[Na+].[Na+]>CN(C)C=O>[CH3:17][N:4]1[C:5]2[C:10](=[CH:9][C:8]([CH3:12])=[C:7]([CH3:13])[CH:6]=2)[N:11]=[C:2]([CH3:1])[C:3]1=[O:14]参加物
5
実験手順
A mixture of 3,6,7-trimethyl-2(1H)-quinoxalinone (5.0 g., 0.027 mol.), methyl iodide (15 ml.), sodium carbonate (5.0 g., 0.047 mol.) and dimethylformamide (75 ml.) were stirred at room temperature for eighteen hours, then heated at 75°-80° C. for three hours. Removal of the dimethylformamide under reduced pressure and dilution with water gave a brown solid. Crystallization from acetone (Darco) gave light tan needles. (2.85 g., m.p. 164-166°, 53%)
後処理
- temperatureheated at 75°-80° C. for three hours
- customRemoval of the dimethylformamide under reduced pressure and dilution with water
- customgave a brown solid
- customCrystallization from acetone (Darco)
- customgave light tan needles
出典と根拠
- ORDレコード
- ord-1465c3f8220f46f694cf298204098fc2
- 出典データセット
- uspto-grants-1980_01
- 特許番号
- US04181724
反応ノート
読み込み中…